On the road to reading the RNA-interference code

@article{Siomi2009OnTR,
  title={On the road to reading the RNA-interference code},
  author={Haruhiko Siomi and Mikiko C. Siomi},
  journal={Nature},
  year={2009},
  volume={457},
  pages={396-404}
}
The finding that sequence-specific gene silencing occurs in response to the presence of double-stranded RNAs has had an enormous impact on biology, uncovering an unsuspected level of regulation of gene expression. This process, known as RNA interference (RNAi) or RNA silencing, involves small non-coding RNAs, which associate with nuclease-containing regulatory complexes and then pair with complementary messenger RNA targets, thereby preventing the expression of these mRNAs. Remarkable progress… Expand
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