On the reported optical activity of amino acids in the Murchison meteorite

@article{Bada1983OnTR,
  title={On the reported optical activity of amino acids in the Murchison meteorite},
  author={Jeffrey L. Bada and John R. Cronin and Ming-shan Ho and Keith A. Kvenvolden and James G. Lawless and Stanley L. Miller and Joan Or{\'o} and Spencer Steinberg},
  journal={Nature},
  year={1983},
  volume={301},
  pages={494-496}
}
In analyses of extracts from the Murchison meteorite (a carbonaceous chondrite), Engel and Nagy1 reported an excess of L-enantiomers for several protein amino acids but found that the non-protein amino acids were racemic. They suggested that the excess of L-isomers might have resulted from an asymmetric synthesis or decomposition. Their results disagree with those obtained previously2–4 and they claim this is due to improved methodology. In fact, their extraction method and analytical procedure… Expand
Summary and implications of reported amino acid concentrations in the Murchison meteorite
TLDR
The possibility of sampling bias needs to be tested experimentally before concluding that extraction is complete, and that the constant relative abundances indicate that the relative concentrations of amino acids are homogeneous in the meteorite. Expand
Molecular and chiral analyses of some protein amino acid derivatives in the Murchison and Murray meteorites
— The varied organic suite extracted from the Murchison meteorite contains several amino acids that are common to the biosphere. Some of these have been found to be non-racemic, but the indigenousExpand
The stereochemistry of amino acids in the Murchison meteorite
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Pathways for the asymmetric amplification of protein amino acids in the Murchison meteorite
The amplification of L-enantiomers of amino acids from racemates was likely a precondition for the origin of life on Earth. Engel and Nagy1 first reported that seven protein amino acids in theExpand
Non-racemic amino acids in the Murray and Murchison meteorites.
TLDR
The alpha-methyl-alpha-amino alkanoic acids could have been significant in the origin of terrestrial homochirality given their resistance to racemization and the possibility for amplification of their enantiomeric excesses suggested by the strong tendency of their polymers to form chiral secondary structure. Expand
A comparative study of the hydroxy acids from the Murchison, GRA 95229 and LAP 02342 meteorites
Abstract The hydroxy acid suites extracted from the Murchison (MN), GRA 95229 (GRA) and LAP 02342 (LAP) meteorites have been investigated for their molecular, chiral and isotopic composition.Expand
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Characteristics and formation of amino acids and hydroxy acids of the Murchison meteorite.
TLDR
The marked structural correspondence between the alpha-amino acids and alpha-hydroxy acids and the high deuterium/hydrogen ratio argue persuasively for their formation by aqueous phase Strecker reactions in the meteorite parent body from presolar. Expand
Origins of the L-amino acid excess in carbonaceous meteorites
  • M. Engel
  • Chemistry, Engineering
  • Optics & Photonics - Optical Engineering + Applications
  • 2012
Carbonaceous meteorites provide the best direct evidence for the types and abundances of organic compounds that were present at approximately the time of formation of our solar system. The occurrenceExpand
Amino acids in carbonaceous meteorites: biotic or abiotic?
Carbonaceous meteorites are relics of ancient parent bodies from the time of formation of our solar system, about 4.5 billion years ago. They contain many of the organic compounds (e.g. amino acids)Expand
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Early determinations of the amino acid distribution in water extracts of the Murchison meteorite revealed unusual amino acids, including isovaline (Ival), α-aminoisobutyric acid (α-Aiba) andExpand
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Abstract Continued investigation of the Murchison meteorite by gas chromatography combined with mass spectrometry has led to the characterization of at least 17 amino acids in addition to the 18Expand
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TLDR
A sensitive method based on the separation of enantiomeric N-trifluoroacetyl (N-TFA)–isopropyl esters by gas chromatography with an optically active stationary phase is developed and applied to meteorites and a Pre-Cambrian sediment. Expand
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TLDR
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