On the relevance of cocaine detection in a fingerprint

@article{Jang2020OnTR,
  title={On the relevance of cocaine detection in a fingerprint},
  author={Min Jang and Catia Costa and Josephine Bunch and B. Gibson and Mahado Ismail and Vladimir Palitsin and Roger Webb and Mark Hudson and M. J. Bailey},
  journal={Scientific Reports},
  year={2020},
  volume={10}
}
The finding that drugs and metabolites can be detected from fingerprints is of potential relevance to forensic science and as well as toxicology and clinical testing. However, discriminating between dermal contact and ingestion of drugs has never been verified experimentally. The inability to interpret the result of finding a drug or metabolite in a fingerprint has prevented widespread adoption of fingerprints in drug testing and limits the probative value of detecting drugs in fingermarks. A… 

A comparative review on detection of Cocaine using hyphenated techniques

Narcotic drugs have analgesic properties due to which they are commonly consumed to relieve pain from the body. The mode of action of these drugs is to depress the central nervous system. Long-term

Interpol Review of Drug Analysis 2019-2022

Advances in mass spectrometry imaging for toxicological analysis and safety evaluation of pharmaceuticals.

This review aims to cover a detailed summary of the various MSI technologies utilized in the biomedical and pharmaceutical area, including technical principles, advantages, current status, and future trends, to provide a reference for pharmaceutical research, improve rational clinical medicine use, and ensure public safety.

Potential to Use Fingerprints for Monitoring Therapeutic Levels of Isoniazid and Treatment Adherence

Fingerprints are a novel and noninvasive approach to monitor INH therapy and can be used as internal markers to demonstrate a sufficient sample volume for testing and reduce intradonor variability.

Probabilistic quotient’s work and pharmacokinetics’ contribution: countering size effect in metabolic time series measurements

The MIX method improves the reliability and robustness of quantitative biomarker detection in finger sweat and other biofluids, paving the way for biomarker discovery and hypothesis generation from metabolomic time course data.

Ambient ion focusing for paper spray ionisation

Microsampling with a Solid-Phase Extraction Cartridge: Storage and Online Mass Spectrometry Analysis.

Results proved that the new syringe-based SPE cartridge can serve as a good alternative to conventional microsampling techniques in terms of analyte stability, ease of operation and versatility, and analytical sensitivity and speed.

Pressure-Sensitive Adhesive Combined with Paper Spray Mass Spectrometry for Low-Cost Collection and Analysis of Drug Residues.

The novel approach demonstrates a simple yet effective sampling strategy, allowing for rapid identification from difficult surfaces via paper spray mass spectrometry.

References

SHOWING 1-10 OF 28 REFERENCES

Distinguishing between Contact and Administration of Heroin from a Single Fingerprint using High Resolution Mass Spectrometry

This research highlights the importance of washing hands prior to donating a fingerprint sample to distinguish recent contact with heroin from heroin use, and detection of morphine, noscapine and acetylcodeine gave a closer agreement to patient testimony on whether they had recently used heroin than the detection of heroin and 6-AM alone.

Mass Spectrometry Methods for the Recovery of Forensic Intelligence from Fingermarks

  • M. BaileyC. Costa
  • Chemistry
    Emerging Technologies for the Analysis of Forensic Traces
  • 2019
Mass spectrometry is a method of identifying molecules within a sample, based on a characteristic mass to charge ratio. Over the last decades, it has become possible to use mass spectrometry to

Emerging trends in paper spray mass spectrometry: Microsampling, storage, direct analysis, and applications.

This critical review will discuss how mass spectrometry has expanded the utility of paper substrates from sample collection and storage, to direct complex mixture analysis to on-surface reaction monitoring.

Paper spray screening and liquid chromatography/mass spectrometry confirmation for medication adherence testing: A two‐step process

A two‐step process of paper spray followed by LC/MS is developed to rapidly screen a large number of samples and confirm any disputed results, which demonstrates the applicability for testing medication adherence from a fingerprint.

Drug screening using the sweat of a fingerprint: lateral flow detection of Δ9-tetrahydrocannabinol, cocaine, opiates and amphetamine

The study shows that there was sufficient sweat present on the fingertips to enable analysis and that the Drug Screening Cartridge could detect the presence, or absence, of each drug.

Fingerprint Drug Analysis: Overcoming Pitfalls and Heading Toward the Future?

The detection of cocaine and/or heroin use is described by mass spectrometric analysis of fingerprints collected on dedicated Whatman paper to control drug trafficking, to ensure proper healthcare, and to provide adequate workplace and forensic drug testing.

The detection and quantification of lorazepam and its 3-O-glucuronide in fingerprint deposits by LC-MS/MS.

Quantitative analysis for the benzodiazepine lorazepam and its 3-O-glucuronide conjugate in fingerprints following the oral administration of a single 2 mg dose of lorzepam to five volunteers indicates the first time a drug glucuronide has been detected in deposited fingerprints.

Time-course measurements of caffeine and its metabolites extracted from fingertips after coffee intake: a preliminary study for the detection of drugs from fingerprints

Fingerprints were a more efficient source for drug testing than other biological samples, such as blood and sweat, because the procedures for sampling and extracting the drugs were simpler and took less time.