On the pH dependence of amide proton exchange rates in proteins.

Abstract

We have analyzed the pH dependencies of published amide proton exchange rates (kex) in three proteins: bovine pancreatic trypsin inhibitor (BPTI), bull seminal plasma proteinase inhibitor IIA (BUSI IIA), and calbindin D9K. The base-catalyzed exchange rate constants (kOH) of solvent exposed amides in BPTI are lower for residues with low peptide carbonyl… (More)

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Cite this paper

@article{Eriksson1995OnTP, title={On the pH dependence of amide proton exchange rates in proteins.}, author={Mats Anders Eriksson and Torleif H{\"a}rd and Lina Nilsson}, journal={Biophysical journal}, year={1995}, volume={69 2}, pages={329-39} }