On the origin of leprosy

@article{Cole2005OnTO,
  title={On the origin of leprosy},
  author={Stewart T. Cole and Marc Monot and Nadine Honoré},
  journal={BMC Proceedings},
  year={2005},
  volume={2},
  pages={1}
}
Leprosy, a chronic human disease with potentially debilitating neurological consequences, results from infection with Mycobacterium leprae. This unculturable pathogen has undergone extensive reductive evolution, with half of its genome now occupied by pseudogenes. Using comparative genomics, we demonstrated that all extant cases of leprosy are attributable to a single clone whose dissemination worldwide can be retraced from analysis of very rare single-nucleotide polymorphisms. The disease… 
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References

References and Notes
our experimentation could eventually be used to discredit our findings, should they happen not to agree with the original observations. It seems important that all experiments in the rapidly