On the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer

@inproceedings{Doig2012OnTO,
  title={On the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer},
  author={Kenneth D. Doig and Kathryn E Holt and Janet A. M. Fyfe and Caroline J. Lavender and Miriam Eddyani and Françoise Portaels and Dorothy Yeboah-Manu and Gerd Pluschke and Torsten Seemann and Timothy P Stinear},
  booktitle={BMC Genomics},
  year={2012}
}
Mycobacterium ulcerans is an unusual bacterial pathogen with elusive origins. While closely related to the aquatic dwelling M. marinum, M. ulcerans has evolved the ability to produce the immunosuppressive polyketide toxin mycolactone and cause the neglected tropical disease Buruli ulcer. Other mycolactone-producing mycobacteria (MPM) have been identified in fish and frogs and given distinct species designations (M. pseudoshottsii, M. shinshuense, M. liflandii and M. marinum), however the… CONTINUE READING
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Nesoni

  • P Harrison, T Seemann
  • Bioinformatics
  • 2011

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