On the origin of EEG-slowing and encephalopathy during induction treatment of acute lymphoblastic leukemia.

@article{Korinthenberg2002OnTO,
  title={On the origin of EEG-slowing and encephalopathy during induction treatment of acute lymphoblastic leukemia.},
  author={Rudolf Korinthenberg and Bernadette Scheuring and Joachim Boos and Charlotte Niemeyer},
  journal={Medical and pediatric oncology},
  year={2002},
  volume={39 6},
  pages={
          566-72
        }
}
BACKGROUND Neurological complications and EEG slowing frequently occur in children undergoing induction treatment for acute lymphoblastic leukemia (ALL). Disease-related factors and treatment-related toxicity are believed to play causative roles. We wanted to elucidate the etiology further by serial EEG examinations and parallel CSF amino acid analyses. PROCEDURE Twenty-nine children participated in the study. EEG examinations with quantitative computerized analysis were scheduled on day 1… CONTINUE READING