On the origin and evolution of the genetic code

@article{JimenezSanchez1995OnTO,
  title={On the origin and evolution of the genetic code},
  author={A. Jimenez-Sanchez},
  journal={Journal of Molecular Evolution},
  year={1995},
  volume={41},
  pages={712-716}
}
Two ideas have essentially been used to explain the origin of the genetic code: Crick's frozen accident and Woese's amino acid-codon specific chemical interaction. Whatever the origin and codon-amino acid correlation, it is difficult to imagine the sudden appearance of the genetic code in its present form of 64 codons coding for 20 amino acids without appealing to some evolutionary process. On the contrary, it is more reasonable to assume that it evolved from a much simpler initial state in… CONTINUE READING

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