On the number of EINECS compounds that can be covered by (Q)SAR models for acute toxicity.

@article{Zvinavashe2009OnTN,
  title={On the number of EINECS compounds that can be covered by (Q)SAR models for acute toxicity.},
  author={Elton Zvinavashe and Albertinka Jacoba Murk and Ivonne M C M Rietjens},
  journal={Toxicology letters},
  year={2009},
  volume={184 1},
  pages={67-72}
}
The new EU legislation for managing chemicals called REACH aims to fill in gaps in toxicity information that exist for the chemicals listed on the European Inventory of Existing Chemical Substances (EINECS). REACH advocates the use of alternatives to animal experimentation including, amongst others, (quantitative) structure-activity relationship models [(Q)SARs] to help fill in the toxicity data gaps. The aim of the present study was to provide a science-based estimate of the number of EINECS… CONTINUE READING