On the nature of thumbs


Asymmetric regulation of Hox gene expression pre-dates the appearance of tetrapod digits, and was co-opted in the development of 'thumbness'. This asymmetric expression correlates with independent morphological evolutionary variation of digit 1.

DOI: 10.1186/gb-2008-9-3-213

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@article{Wagner2008OnTN, title={On the nature of thumbs}, author={G{\"{u}nter P. Wagner and Alexander Vargas}, journal={Genome Biology}, year={2008}, volume={9}, pages={213 - 213} }