On the metabolic role of thymidine 2′‐hydroxylase (thymidine, 2‐oxoglutarate: Oxygen oxidoreductase, EC 1.14.11.3) in Neurospora crassa
@article{Bankel1976OnTM, title={On the metabolic role of thymidine 2′‐hydroxylase (thymidine, 2‐oxoglutarate: Oxygen oxidoreductase, EC 1.14.11.3) in Neurospora crassa}, author={L. Bankel and G. Lindstedt and S. Lindstedt}, journal={FEBS Letters}, year={1976}, volume={71} }
The 2’.hydroxylation of thymidine was first described by Shaffer et al. [2] in the course of a study of thymine metabolism in cell extracts from a NeurOSpOrQ crassa strain. The product of this reaction is ribosylthymide [3]. Studies of a mutant strain from Neurospora crassa devoid of thymine 7-hydroxylase activity [4] as well as protein fractionation studies [4,5] demonstrated that thymidine 2’hydroxylase (thymidine, 2-oxoglutarate: oxygen oxidoreductase, EC 1 .I 4.11.3) was separate from… Expand
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Thymine 7-hydroxylase from Neurospora crassa. Substrate specificity studies.
- Chemistry, Medicine
- Biochimica et biophysica acta
- 1977
- 14
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