On the mechanism of radiosensitization by 5-bromouracil

  • Gerhart Hotz
  • Published 1968 in Molecular and General Genetics MGG


Experimental evidence for the sensitization of broth-suspended phage ϕX-174 and its single-stranded infectious DNA by incorporation of 5-bromouracil against ionizing radiation is given. No influence of phage protein or molecular DNA-structure on the amount of BU-damage has been observed. The absence of desensitization by radical-scavenging compounds like… (More)
DOI: 10.1007/BF00341869


3 Figures and Tables