On the mechanism of leftward frameshifting at several hungry codons.

@article{Barak1996OnTM,
  title={On the mechanism of leftward frameshifting at several hungry codons.},
  author={Z Barak and D. Lindsley and Jonathan Gallant},
  journal={Journal of molecular biology},
  year={1996},
  volume={256 4},
  pages={
          676-84
        }
}
We have used lacZ reporter genes to assess leftward ribosome frameshifting on sequences containing the quadruplet U UUC followed by several different triplets coding for lysine, isoleucine, or leucine. Limitation for lysine-tRNA provokes leftward frameshifting when the slippery quadruplet is followed by either lysine codon aag or aaa, but not when followed by an isoleucine or leucine codon. Limitation for isoleucine provokes frameshifting when the quadruplet is followed by either isoleucine… Expand
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  • J. Gallant, D. Lindsley
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1998
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