On the mechanism of alkylphosphocholine (APC)-induced apoptosis in tumour cells.

@article{Oberle2005OnTM,
  title={On the mechanism of alkylphosphocholine (APC)-induced apoptosis in tumour cells.},
  author={Carolin Oberle and Ulrich Massing and Harald F Krug},
  journal={Biological chemistry},
  year={2005},
  volume={386 3},
  pages={237-45}
}
Alkylphosphocholines (APCs) represent a new and very encouraging class of antitumour agents that have also been shown to induce apoptosis in tumour cells, but their exact mode of action has still not been elucidated. The APC compound presented here, S-1-O-phosphocholine-2- N-acetyl-octadecane (S-NC-2) induces apoptosis in a variety of cancer cells. To… CONTINUE READING