On the immortality of the germ line: genetic and biochemical mechanism. A review.

@article{Medvedev1981OnTI,
  title={On the immortality of the germ line: genetic and biochemical mechanism. A review.},
  author={Zh A Medvedev},
  journal={Mechanisms of ageing and development},
  year={1981},
  volume={17 4},
  pages={331-59}
}
  • Zh A Medvedev
  • Published 1981 in Mechanisms of ageing and development
The nature of the differences between mortal somatic cells and immortal germ cell lines constitutes a major area of theoretical gerontology which has not yet received adequate attention. Weismann's theory, first stated almost exactly a century ago, was recently reconsidered by Kirkwood and Holliday. They applied modern concepts and findings on the factors regulating the accuracy of synthesis of macromolecules to explain germ line immortality. In the present paper, evidence on ageing of… CONTINUE READING