On the frequency limit and phase of outer hair cell motility: effects of the membrane filter.

@article{SantosSacchi1992OnTF,
  title={On the frequency limit and phase of outer hair cell motility: effects of the membrane filter.},
  author={Joseph Santos-Sacchi},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1992},
  volume={12 5},
  pages={1906-16}
}
Whole-cell voltage clamp and displacement-measuring photodiode techniques were used to study electrophysiological and mechanical properties of the guinea pig outer hair cell (OHC). OHCs demonstrate a voltage-mechanical response (V-M) function that can be fit by a two state Boltzmann relation, where the cell normally rests near the hyperpolarizing saturation region (-70 to -90 mV). The voltage at half-maximal length change (Vh) is depolarized relative to the resting potential, and this ensures… CONTINUE READING