On the failure of azo-gelatin as an antigen.

@article{Haurowitz1943OnTF,
  title={On the failure of azo-gelatin as an antigen.},
  author={Felix Haurowitz and M Tunca and Paula Schwerin},
  journal={The Biochemical journal},
  year={1943},
  volume={37 2},
  pages={
          249-50
        }
}
The non-antigenicity of gelatin was attributed for a long time to its lack of aromatic amino-acids. Later, Landsteiner [1919] and Hooker & Boyd [1932] introduced aromatic determinant groups into the gelatin molecule by coupling it with diazotized arsanilic acid. Injection of arsanil-azo-gelatin into rabbits furnished inmmune sera which gave slight precipitates with the arsanil-azo-compounds of casein, ovalbumin and serum-globulin, but gave no visible reaction with arsanil-azo-gelatin. Similar… Expand
Non-antigenicity of Gelatin
INTEREST in the inability of gelatin to act as a full antigen, that is, to produce specific anti-bodies when injected into an animal, has been revived by the observations of Haurowitz, Tunca andExpand
Nature of Retained Antigen and Its Role in Immune Mechanisms
TLDR
Characterization of retained antigen (physical properties and biological properties) and retained antigen and antibody formation is also discussed in this chapter. Expand
A site of action of streptomycin.
  • W. Umbreit
  • Chemistry, Medicine
  • The Journal of biological chemistry
  • 1949
TLDR
The mode of action of streptomycin is traced with the object of determining what reactions vital to the cell are interfered with, and which reactions of the bacterium are susceptible to strePTomycin inhibition at concentrations of this agent which seem to be effective in practice. Expand
Antigene, Antikörper und Komplement
Immunitat wurde zuerst als ein medizinisches Phanomen beschrieben, als Immunitat gegen pathogene Erreger. Das immunisierende Agens, zumeist ein pathogenes Bacterium, wurde als Antigen bezeichnet, dieExpand
THE MECHANISM OF THE IMMUNOLOGICAL RESPONSE
Anaphylactogenic properties of gelatin and its precursors.
CLINICAL SENSITIVITIES TO GELATIN AND OTHER MEAT PRODUCTS

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1931] found that vitamin 'G'deficient rats showed eye changes which they described as 'a very slight keratitis with corneal corpuscles, a few polymorphs
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