On the existence of functional beta-adrenoceptors on vascular sympathetic nerve endings in the human forearm.

@article{Chang1994OnTE,
  title={On the existence of functional beta-adrenoceptors on vascular sympathetic nerve endings in the human forearm.},
  author={Peter C. Chang and Ehud Grossman and Irwin J. Kopin and David S Goldstein},
  journal={Journal of hypertension},
  year={1994},
  volume={12 6},
  pages={681-90}
}
OBJECTIVE To examine the existence of presynaptic beta-adrenoceptors modulating forearm norepinephrine release in 31 healthy volunteers. METHODS The spillover rate of norepinephrine in forearm venous plasma and the total plasma appearance rate of norepinephrine in the forearm were estimated using intra-arterial infusion of [3H]-norepinephrine. Isoprenaline was infused intra-arterially to stimulate beta-adrenoceptors, terbutaline to stimulate beta 2-adrenoceptors, propranolol to block beta… CONTINUE READING
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