On the evocability of a positive oestrogen feedback action on LH secretion in female and male rats.

Abstract

Following a single injection of oestradiol benzoate (15 mug/100 g body weight) postpubertally castrated and oestrogen-primed female rats showed a distinct surge of LH secretion, while castrated and androgen-primed females displayed a diminished and delayed surge of LH secretion. On the other hand, postpubertally castrated and oestrogen-primed male rats exhibited only a slight, but significant surge of LH secretion, whereas castrated and androgen-primed males did not display any surge of LH secretion following oestrogen injection. In view of these findings the evocability of a positive oestrogen feedback action on LH secretion is dependent on the sex hormone level during the critical hypothalamic differentiation phase and the functional (priming) phase as well.

Cite this paper

@article{Drner1975OnTE, title={On the evocability of a positive oestrogen feedback action on LH secretion in female and male rats.}, author={G{\"{u}nter D{\"{o}rner and Franziska Goetz and Wolfgang Rohde}, journal={Endokrinologie}, year={1975}, volume={66 3}, pages={369-72} }