On the edge: pharmacological evidence for anxiety-related behavior in zebrafish larvae.

@article{Richendrfer2012OnTE,
  title={On the edge: pharmacological evidence for anxiety-related behavior in zebrafish larvae.},
  author={Holly A Richendrfer and Sean D Pelkowski and Ruth M. Colwill and Robbert Cr{\'e}ton},
  journal={Behavioural brain research},
  year={2012},
  volume={228 1},
  pages={99-106}
}
Zebrafish larvae are ideally suited for high-throughput analyses of vertebrate behavior. The larvae can be examined in multiwell plates and display a range of behaviors during early development. Previous studies have shown that zebrafish larvae display a preference for the edge of the well and several lines of evidence suggest this edge preference (thigmotaxis) may be a measure of anxiety. In the present study, we further examined the relation between edge preference and anxiety by imaging… CONTINUE READING

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