On the directional specificity of ribosome frameshifting at a "hungry" codon.

@article{Lindsley1993OnTD,
  title={On the directional specificity of ribosome frameshifting at a "hungry" codon.},
  author={Donald H. Lindsley and Jonathan Gallant},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 12},
  pages={
          5469-73
        }
}
Limitation for aminoacyl-tRNA promotes ribosome frameshifting at certain sites. We have previously demonstrated ribosome frameshifting to the right (3') at an AAG site in one context, and to the left (5') at an AAG site in a different context. Here, we demonstrate that the "rightwing" context is largely specific for frameshifting to the right, and the "leftwing" context is largely specific for frameshifting to the left. Analysis of these context rules, and the conversion of a sequence that… CONTINUE READING

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