On the determination of phenylalanine hydroxylase activity in crude liver extracts.

@article{Christensen1962OnTD,
  title={On the determination of phenylalanine hydroxylase activity in crude liver extracts.},
  author={P. Christensen},
  journal={Scandinavian journal of clinical and laboratory investigation},
  year={1962},
  volume={14},
  pages={
          623-8
        }
}
  • P. Christensen
  • Published 1962
  • Chemistry, Medicine
  • Scandinavian journal of clinical and laboratory investigation
The phenylalanine hydroxylating system.
  • S. Kaufman
  • Medicine, Chemistry
  • Advances in enzymology and related areas of molecular biology
  • 1993
Demonstration of two forms of phenylalanine hydroxylase in human liver obtained at autopsy.
TLDR
Phenylalanine hydroxylase has been demonstrated to be present in human liver obtained at autopsy and its properties suggest that it is bound to a membrane via a lipid linkage. Expand
Daily variations in phenylalanine hydroxylase activity in male and female guinea pigs
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Female guinea pigs showed variations in plasma phenylalanine and tyrosine which were similar to those observed over the same period for male animals, but not in female animals. Expand
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The chronic effects of the pesticide dieldrin on metabolic pathways in the rainbow trout (Salmo gairdneri) are described and one of the most prevalent pesticides in the aquatic environment is described. Expand
Phenylalanine hydroxylase of Macaca irus. Purification of two components of the enzyme.
  • R. Cotton
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 1971
TLDR
Phenylalanine hydroxylase has been purified up to 424-fold from the liver of the Cynomolgus monkey after stabilization of the enzyme during extraction and chromatography. Expand
The phenylalanine hydroxylating system from mammalian liver.
  • S. Kaufman
  • Chemistry, Medicine
  • Advances in enzymology and related areas of molecular biology
  • 1971
Rat Liver Phenylalanine Hydroxylase
The activity of rat liver phenylalanine hydroxylase has been measured in systems which, in addition to the components necessary for hydroxylation, contained ascorbic acid and catalase.Expand
THE NATURE OF IN VITRO HYDROXYLATION OF l‐TRYPTOPHAN BY BRAIN TISSUE
TLDR
The present study describes the occurrence and localization of and the conditions affecting the hydroxylation irt vitro of tryptophan in brain tissue. Expand
The phenylalanine hydroxylase content of livers of various vertebrates.
TLDR
The rat possesses the highest activity of all the mammals studied, and no correlation exists between enzyme activity and animal weight or phylogenetic classification. Expand
Neuere Untersuchungen über zentral wirkende endogene endogene Amine
Untersuchungen wahrend der letzten funf Jahre haben unsere Kenntnisse uber den Stoffwechsel und die Bedeutung der endogenen peripher und zentral wirkenden Amine erheblich erweitert. ModerneExpand
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References

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A new cofactor required for the enzymatic conversion of phenylalanine to tyrosine.
  • S. Kaufman
  • Medicine, Chemistry
  • The Journal of biological chemistry
  • 1958
The chemical estimation of tyrosine and tyramine.
TLDR
1-Nitroso-2-naphthol reacts with both tyrosine and tyramine to form a red-colored product which gradually changes to a stable yellow chromo- phore and has been isolated. Expand
The enzymatic conversion of phenylalanine to tyrosine.
The conversion of phenylalanine to tyrosine in normal rats.
TLDR
The excretion of homogentisic acid by rats after administration of large doses of phenylalanine and by guinea pigs and humans after ingestion of tyrosine seems to indicate that both amino acids travel similar pathways during degradation. Expand
Metabolic studies in phenylketonuria.