On the design of synthetic case-control studies.

  title={On the design of synthetic case-control studies.},
  author={Ross L. Prentice},
  volume={42 2},
A design is proposed for "case-control within cohort" studies. In this design, controls are sampled without replacement from failure-free members of the cohort at each distinct failure time. Upon selection, a subject ceases to be eligible for control selection at later failure times. Also, if a subject failing at time t had been selected as a control at t' less than t, then the matched controls at t are selected to have also been at risk at t'. In these circumstances correlation exists between… CONTINUE READING
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