On the control of the trophoblastic giant-cell transformation in the mouse: homotypic cellular interactions and polyploidy.

  • Edward B. Ilgren
  • Published 1981 in Journal of embryology and experimental morphology


Trophoblastic tissues grown under different conditions in vitro display distinct patterns of cellular growth. Thus, trophoblast cultured on 'bacteriological grade' plastic surfaces remained in suspension culture as rounded tissue fragments. Such tissues maintained numerous cell contacts and remained, in turn, largely diploid. Trophoblast explanted on a… (More)


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