On the classes of aminoacyl-tRNA synthetases and the error minimization in the genetic code.

@article{Cavalcanti2000OnTC,
  title={On the classes of aminoacyl-tRNA synthetases and the error minimization in the genetic code.},
  author={Andr{\'e} R. O. Cavalcanti and Brenno A D Neto and Ricardo Pinto Ferreira},
  journal={Journal of theoretical biology},
  year={2000},
  volume={204 1},
  pages={15-20}
}
As a consequence of the existence of two classes of aminoacyl-tRNA synthetases (aaRSs), we defined two types of mutations: g (mutations that do not change the class of the involved amino acids) and u (those which change the class). We have found that the mean chemical distance resulting from g mutations is smaller than that corresponding to u mutations… CONTINUE READING