On the binding of iabelled saxitoxin to the squid giant axon

@article{Keynes1984OnTB,
  title={On the binding of iabelled saxitoxin to the squid giant axon},
  author={R. Keynes and J. Ritchie},
  journal={Proceedings of the Royal Society of London. Series B. Biological Sciences},
  year={1984},
  volume={222},
  pages={147 - 153}
}
  • R. Keynes, J. Ritchie
  • Published 1984
  • Chemistry, Medicine
  • Proceedings of the Royal Society of London. Series B. Biological Sciences
  • Measurement of the maximum saturable binding capacity for 3H-labelled saxitoxin in well cleaned giant axons from Loligo forbesi gave a value of 290 ± 65 (s. e. m.) binding sites per square micrometre of membrane. In samples of the fin nerve the total saturable uptake was 12.4 ± 2.4 fmol mg-1 wet mass, corresponding to 94 sites per square micrometre for fibres whose mean diameter after fixation and embedding was estimated as 16 µm. 
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