On the basic computational structure of gene regulatory networks.

  title={On the basic computational structure of gene regulatory networks.},
  author={Carlos Rodr{\'i}guez-Caso and Bernat Corominas-Murtra and Ricard V. Sol{\'e}},
  journal={Molecular bioSystems},
  volume={5 12},
Gene regulatory networks constitute the first layer of the cellular computation for cell adaptation and surveillance. In these webs, a set of causal relations is built up from thousands of interactions between transcription factors and their target genes. The large size of these webs and their entangled nature make it difficult to achieve a global view of their internal organisation. Here, this problem has been addressed through a comparative study of Escherichia coli, Bacillus subtilis and… CONTINUE READING


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