On the accuracy of Monte Carlo based beam dynamics models for the degrader in proton therapy facilities

  title={On the accuracy of Monte Carlo based beam dynamics models for the degrader in proton therapy facilities},
  author={Valeria Rizzoglio and Andreas Adelmann and Christian Baumgarten and David Meer and Jochem Snuverink and Vadim Talanov},
  journal={Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment},
  • V. Rizzoglio, A. Adelmann, V. Talanov
  • Published 1 December 2017
  • Physics
  • Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Geometry optimisation of graphite energy degrader for proton therapy.
  • E. Oponowicz, H. L. Owen, S. Psoroulas, D. Meer
  • Physics, Medicine
    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics
  • 2020
Uncertainty quantification analysis and optimization for proton therapy beam lines.
Design of a light and fast energy degrader for a compact superconducting gantry with large momentum acceptance.
Simulation of dose distribution and secondary particle production in proton therapy of brain tumor.
  • Zahra Hashemi, M. Tatari, H. Naik
  • Medicine, Physics
    Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
  • 2020
Study of intensity suppression in a gantry beamline for SC200 proton therapy system
ABSTRACT For proton therapy, a beam intensity of 0.4 nA to 4 nA is typically used with a beam transmission factor of 10. However, because of energy degrading, emittance matching, and energy spread
Dynamic beam current control for improved dose accuracy in PBS proton therapy.
This work introduced dynamic beam current control at the PSI Gantry 2, an innovative new approach successfully commissioned and in clinical operation since fall 2017, and shows by two independent and complementary methods that the delivered dose distribution is improved.
OPAL a Versatile Tool for Charged Particle Accelerator Simulations
Many sophisticated computer models have been developed to understand the behaviour of particle accelerators. Even these complex models often do not describe the measured data. Interactions of the
Investigation of multi-intensity compensation for a medical proton therapy facility using the quadrupole scanning method
  • Xian-Hu Zeng, Yuntao Song, Lei Zhu
  • Physics
    Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
  • 2019
In this work we present the new target assembly developed for solid samples irradiation by protons with different energies at maximum of 11 MeV and 40 μA for current. The new target was designed and
Current Delivery Limitations of Proton PBS for FLASH.
  • W. Zou, E. Diffenderfer, Lei Dong
  • Physics, Medicine
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
  • 2020


Evolution of a beam dynamics model for the transport line in a proton therapy facility
Despite the fact that the first-order beam dynamics models allow an approximated evaluation of the beam properties, their contribution is essential during the conceptual design of an accelerator or
Geant4 simulations of proton beam transport through a carbon or beryllium degrader and following a beam line.
It is found that the degrader does not completely erase the initial beam phase space even at low degraded beam energies, and an improvement in the transmission of 30-45%, depending on the degraded beam energy, the higher value for the lower energies.
The FLUKA Code: An Accurate Simulation Tool for Particle Therapy
Refinements of the FLUKA nuclear models in the therapeutic energy interval lead to an improved description of the mixed radiation field as shown in the presented benchmarks against experimental data with both 4He and 12C ion beams.
Measurements and simulations of boron carbide as degrader material for proton therapy.
Test measurements using boron carbide (B4C) as degrader material in comparison with the conventional graphite, which is currently used in many proton therapy degraders, predict a higher beam transmission, especially at low beam energies.
Neutron doses due to beam losses in a novel concept of a proton therapy gantry
It has been found that compared with a conventional gantry the expected additional dose is higher but the optimization of the beam line configuration and additional shielding shall help to reduce the dose to an acceptable value.
Accurate Monte Carlo simulations for nozzle design, commissioning and quality assurance for a proton radiation therapy facility.
The Monte Carlo nozzle model was used to study mechanical optimization in terms of scattered radiation and secondary radiation in the design of the nozzles, and the sensitivity of dose distributions in water with respect to various beam parameters and geometrical misalignments is presented.
Beam Delivery Simulation: BDSIM - Automatic Geant4 Models of Accelerators
Beam Delivery Simulation (BDSIM) is a program that uses a suite of high energy physics software including Geant4, CLHEP & ROOT, that seamlessly tracks particles through accelerators and detectors
On the scattering power of radiotherapy protons.
An improved "differential Molière" formula for scattering power T(dM) is derived by including a nonlocal correction factor fdM which parametrizes the single scattering correction (SSC) and is easily computed and generalizes readily to mixed slabs because fdD is not material dependent.
Proton therapy physics
Proton Therapy: History and Rationale, Harald Paganetti Physics of Proton Interactions in Matter, Bernard Gottschalk Proton Accelerators, Marco Schippers Characteristics of Clinical Proton Beams,