On the Relationship between Sialomucin and Sulfomucin Expression and Hydrogenotrophic Microbes in the Human Colonic Mucosa

@inproceedings{Croix2011OnTR,
  title={On the Relationship between Sialomucin and Sulfomucin Expression and Hydrogenotrophic Microbes in the Human Colonic Mucosa},
  author={Jennifer A. Croix and Franck Carbonero and Gerardo M. Nava and Mark Russell and Eugene Greenberg and H. Rex Gaskins},
  booktitle={PloS one},
  year={2011}
}
The colonic mucus layer is comprised primarily of acidomucins, which provide viscous properties and can be broadly classified into sialomucins or sulfomucins based on the presence of terminating sialic acid or sulfate groups. Differences in acidomucin chemotypes have been observed in diseases such as colorectal cancer and inflammatory bowel disease, and variation in sialo- and sulfomucin content may influence microbial colonization. For example, sulfate derived from sulfomucin degradation may… CONTINUE READING

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