On the Pathogenesis of Sarcoidosis
@article{Shelley1971OnTP, title={On the Pathogenesis of Sarcoidosis}, author={WalterB. Shelley}, journal={Southern Medical Journal}, year={1971}, volume={64}, pages={988-991} }
This review of a most intriguing disease informs the reader of what is known of its possible pathogenesis and also indicates the gaps in knowledge still to be filled in.
36 Citations
Sarcoidosis: Still a Mystery?
- MedicineProceedings
- 2001
Sarcoidosis is a diagnosis of exclusion established by clinical manifestations, radiologic findings, and histologic evidence of noncaseating epithelioid-cell granulomas in >1 organ.
Immunological abnormalities in sarcoidosis.
- Medicine, BiologyAsian Pacific journal of allergy and immunology
- 1984
Sarcoidosis is a systemic granulo matous disease of unknown aetio logy associated with a broad range of immunological abnormalities in both the cell-mediated and humoral limbs of the immune re sponse.
Granulomatous hepatitis in a patient with Crohn's disease and cholestasis
- MedicineBMJ Case Reports
- 2017
We describe a case of a 23-year-old woman with a history of Crohn's disease (CD), who initially presented with sepsis-like symptoms, subsequently developed severe cholestasis and following extensive…
Reduced Prevalence of Smokers in Sarcoidosis
- MedicineAnnals of the New York Academy of Sciences
- 1986
In an earlier study, a smaller percentage of smokers in a cohort of sarcoidosis patients than in the general population was found, and this point was reinvestigated using matched controls.
Pathogenetic mechanism of oral granulomatous diseases: An update
- MedicineJournal of family medicine and primary care
- 2020
Understanding various pathogenic mechanisms underlying various granulomatous conditions affecting oral tissues which mainly revolve around inflammatory cells such as macrophages, T lymphocytes, and genetic mutations might aid in devising treatment modalities without having significant side-effects or morbidity in affected subjects.
Sarcoidosis and the Th 1 chemokine MIG
- Medicine
- 2018
Granulomatous inflammation is characterized by a Type-1 helper (Th1)-mediated immune response with accumulation of macrophages, monocytes, and activated immune cells in granuloma annulare.
Imbalance of pro- and anti-inflammatory cytokines in pulmonary sarcoidosis
- Medicine, BiologyMediators of inflammation
- 1996
Aetiology identical with tuberculosis or closely related to it’, however, proof of this hypothesis remains A number of the characteristics of the disease elusive. Nevertheless, there is an ongoing…
Imbalance of pro-and anti-inflammatory cytokines in pulmonary sarcoidosis
- Medicine, Biology
- 2014
Aetiology identical with tuberculosis or closely related to it’, however, proof of this hypothesis remains A number of the characteristics of the disease elusive. Nevertheless, there is an ongoing…
Sarcoidosis: Immunopathogenesis and Immunological Markers
- Medicine, BiologyInternational journal of chronic diseases
- 2013
The immunological features of sarcoidosis are outlined, the evidence for and against various candidate etiological agents (infective and noninfective), the exhaled breath condensate is described, and a novel method of identifying immunological biomarkers is described to better characterise the immunopathogenesis of sarCOidosis.
Differential Detection of IL-1βand TNF-α mRNA on Lung Macrophages from Patients with Pulmonary Sarcoidosis
- Medicine
- 2009
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