On the Origin of the Canonical Nucleobases: An Assessment of Selection Pressures across Chemical and Early Biological Evolution.

@article{Ros2013OnTO,
  title={On the Origin of the Canonical Nucleobases: An Assessment of Selection Pressures across Chemical and Early Biological Evolution.},
  author={Andro C R{\'i}os and Yitzhak Tor},
  journal={Israel journal of chemistry},
  year={2013},
  volume={53 6-7},
  pages={469-483}
}
The native bases of RNA and DNA are prominent examples of the narrow selection of organic molecules upon which life is based. How did nature "decide" upon these specific heterocycles? Evidence suggests that many types of heterocycles could have been present on the early Earth. It is therefore likely that the contemporary composition of nucleobases is a… CONTINUE READING