On the Nature of Allosteric Transitions: a Plausible Model.

@article{Monod1965OnTN,
  title={On the Nature of Allosteric Transitions: a Plausible Model.},
  author={Jacques Monod and Jeffries Wyman and Jean Pierre Changeux},
  journal={Journal of molecular biology},
  year={1965},
  volume={12},
  pages={88-118}
}
"It is certain that all bodies whatsoever, though they have no sense, yet they have perception; for when one body is applied to another, there is a kind of election to embrace that which is agreeable, and +'0 exclude or expel that which is ingrate; and whether the body be alterant or alterec, evermore a perception precedeth operation; for else all bodies would be like one to another." Francis Bacon (abou.1620) 
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