On the Molecular Pharmacology of the Melanocortin-4 Receptor

@inproceedings{Nijenhuis2003OnTM,
  title={On the Molecular Pharmacology of the Melanocortin-4 Receptor},
  author={Wouter Albertus Johannes Nijenhuis},
  year={2003}
}
Melanocortins are peptide hormones which affect several physiological processes, such as pigmentation, adrenal steroid production, grooming behaviour, nerve regeneration, inflammation and body weight regulation. At least five receptors exist that mediate the effects of melanocortins. The melanocortin receptors belong to the large family of G protein-coupled receptors (GPCRs) and all activate Gs, resulting in increased intracellular cyclic AMP levels. Not for all effects of melanocortins, the… CONTINUE READING

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