On the Mechanism of Beta-oxidation of Long Chain Fatty Acids by Liver Mitochondria from Normal and Alloxan-diabetic Rats.

An accepted mechanism for mitochondrial oxidation of fatty acids, i.e. ,8 oxidation, although inferred to apply also to long chain fatty acids (>C&), has actually been elucidated only for relatively short chain acids (<C’S); only the activation (acyl coenzyme A synthetase) and initial dehydrogenation (acyl coenzyme A dehydrogenase) steps have been… CONTINUE READING