On the Dynamics of the Irreversible Michaelis-menten Reaction Mechanism

@inproceedings{Palsson2001OnTD,
  title={On the Dynamics of the Irreversible Michaelis-menten Reaction Mechanism},
  author={Bernhard 0. Palsson},
  year={2001}
}
The mass action kinetic model of the irreversible Michael&Menten reaction mechanism is mathematically intractable: an explicit analytical solution cannot be obtained. This difficulty is overcome by applying simplifying kinetic assumptions but a full understanding of their dynamic implications and applicability is not readily available. This paper shows how simple modal analysis can provide both a conceptually appealing insight into the reaction dynamics and justification of the commonly used… CONTINUE READING
13 Citations
20 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 20 references

Mathematical modetling of dynamics and control in metabolic networks, Ph.D. Thesis, University of Wisconsin-Madison

  • B. Palsson
  • 1984
Highly Influential
9 Excerpts

The role of dimensionless parameters in the BriggsHaldane and Michaelis - Menten approximations

  • P. S. Crooke
  • Chem . Enana Sci .
  • 1979

1978a, On the kinetics of enzyme action

  • Darvey, G 1., A. H. Klotz, M. Ritter
  • Bull. Math. Biol
  • 1978

An approximate solution of the Michaelis-Menten Mechanism for quasi-steady state and quasi-equilibrium

  • W. Meiske
  • Math. Biosci
  • 1978
1 Excerpt

On the kinetics of enzyme action

  • A. H. Klotz, M. Ritter
  • Bull . Math . Biol .
  • 1978

Doesany enzyme follow the Michaelis-Menten equation

  • C. M. Hill, D Waight.R., W. G. Bardsley
  • Molec. cell. Biochem
  • 1977
1 Excerpt

Similar Papers

Loading similar papers…