On the Allocation of Treatments in Sequential Medical Trials

@inproceedings{Bather1985OnTA,
  title={On the Allocation of Treatments in Sequential Medical Trials},
  author={J. A. Bather},
  year={1985}
}
Summary Several allocation rules are compared by assessing their effectiveness in discovering which of two treatments has the higher probability of success. The number of observations needed to obtain a given level of precision can be minimized by using a fixed-sample rule, but this involves too many applications of the inferior treatment. It is demonstrated that sequential allocation rules can achieve a similar pattern of error probabilities for a small fraction of the expected cost to the… CONTINUE READING