On the Activation of Calcium-Dependent Proteolysis in Brain Neurons of Spontaneously Hypertensive Rats (SHR Strain)

@article{Zakharov2011OnTA,
  title={On the Activation of Calcium-Dependent Proteolysis in Brain Neurons of Spontaneously Hypertensive Rats (SHR Strain)},
  author={Vladislav V Zakharov and Yu. K. Abramova and Mark I. Mosevitsky},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2011},
  volume={150},
  pages={587-589}
}
Females of spontaneously hypertensive (SHR strain) and normotensive rats (WKY strain and Wistar) received drinking water with normal (80 mg/liter) or reduced concentration of Ca2+ (8 mg/liter). Activity of calcium-dependent calpain protease in neurons did not differ in 18-dayold rat pups born and suckled by these animals. Our results are consistent with published data on normal metabolism of SHR rats up to the age of 30 days.