On stand by: host genetics of HIV control.

  title={On stand by: host genetics of HIV control.},
  author={Mary N Carrington and Arman A. Bashirova and Paul J. McLaren},
  volume={27 18},
The impact of host genetic variation on determining the differential outcomes after HIV infection has been studied by two approaches: targeting of candidate genes and genome-wide association studies (GWASs). The overlap in genetic variants that has been identified by these two means has essentially been restricted to variants near to the human leukocyte antigen (HLA) class I genes, although variation in the CCR5 locus, which was first shown to have an effect on HIV outcomes using the candidate… CONTINUE READING