# On spatial and temporal multilevel dynamics and scaling effects in epileptic seizures

@article{Kuehn2011OnSA, title={On spatial and temporal multilevel dynamics and scaling effects in epileptic seizures}, author={C. Kuehn and C. Meisel}, journal={arXiv: Neurons and Cognition}, year={2011} }

Epileptic seizures are one of the most well-known dysfunctions of the nervous system. During a seizure, a highly synchronized behavior of neural activity is observed that can cause symptoms ranging from mild sensual malfunctions to the complete loss of body control. In this paper, we aim to contribute towards a better understanding of the dynamical systems phenomena that cause seizures. Based on data analysis and modelling, seizure dynamics can be identified to possess multiple spatial scales… CONTINUE READING

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#### References

##### Publications referenced by this paper.

SHOWING 1-10 OF 109 REFERENCES

Spatio-temporal dynamics prior to neocortical seizures: amplitude versus phase couplings

- Medicine, Psychology
- 2003

129

Dynamics of non-convulsive epileptic phenomena modeled by a bistable neuronal network

- Medicine, Biology
- 2004

251

From baseline to epileptiform activity: a path to synchronized rhythmicity in large-scale neural networks.

- Medicine, Physics
- 2008

55

A unifying explanation of primary generalized seizures through nonlinear brain modeling and bifurcation analysis.

- Medicine, Psychology
- 2006

354

Transitions to spike-wave oscillations and epileptic dynamics in a human cortico-thalamic mean-field model

- Mathematics, Medicine
- 2009

55

Dynamics of large-scale brain activity in normal arousal states and epileptic seizures.

- Medicine, Physics
- 2002

347

Dynamics of epileptic phenomena determined from statistics of ictal transitions

- Medicine, Computer Science
- 2006

121

New observations may inform seizure models: very fast and very slow oscillations.

- Biology, Medicine
- 2011

18

Long-term variability of global statistical properties of epileptic brain networks.

- Mathematics, Medicine
- 2010

47