On primary structure and biosynthesis of histidine-rich polypeptide from malarial parasite Plasmodium lophurae.

A. Kilejian; T. Liao; W. Trager

DOI:10.1073/PNAS.72.8.3057

Corpus ID: 39617639

On primary structure and biosynthesis of histidine-rich polypeptide from malarial parasite Plasmodium lophurae.

@article{Kilejian1975OnPS,
  title={On primary structure and biosynthesis of histidine-rich polypeptide from malarial parasite Plasmodium lophurae.},
  author={A. Kilejian and T. Liao and W. Trager},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1975},
  volume={72 8},
  pages={
          3057-9
        }
}

A. Kilejian, T. Liao, W. Trager

Published 1975

Biology, Medicine

Proceedings of the National Academy of Sciences of the United States of America

Experiments on the primary structure of a histidine-rich polypeptide isolated from the malarial parasite Plasmodium lophurae indicate that the smaller quantities of amino acids other than histidine form an integral part of the polypeptide and do not arise from a protein contaminating a histidine homopolymer. In culture, the parasites incorporate over 50% of exogenously supplied histidine into the histidine-rich polypeptide and this incorporation is inhibited by puromycin.

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