On noise processes and limits of performance in biosensors

@inproceedings{Hassibia2007OnNP,
  title={On noise processes and limits of performance in biosensors},
  author={Arjang Hassibia and Ali Hajimiri},
  year={2007}
}
In this paper, we present a comprehensive stochastic model describing the measurement uncertainty, output signal, and limits of detection of affinity-based biosensors. The biochemical events within the biosensor platform are modeled by a Markov stochastic process, describing both the probabilistic mass transfer and the interactions of analytes with the capturing probes. To generalize this model and incorporate the detection process, we add noisy signal transduction and amplification stages to… CONTINUE READING
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