On-line sorting of human chromosomes by centromeric index, and identification of sorted populations by GTG-banding and fluorescent in situ hybridization

@article{Boschman1990OnlineSO,
  title={On-line sorting of human chromosomes by centromeric index, and identification of sorted populations by GTG-banding and fluorescent in situ hybridization},
  author={Gert A. Boschman and W. Rens and Eric Manders and Carel van Oven and Gerrit W. Barendsen and J. A. Aten},
  journal={Human Genetics},
  year={1990},
  volume={85},
  pages={41-48}
}
Using slit-scan flow cytometry, the shape of human metaphase chromosomes, as expressed in their centromeric index (CI), and the DNA content of the chromosomes have been used as parameters in bivariate flow karyotyping. The resolution of the DNA vs CI flow karyogram of the larger chromosomes up to chromosome 13 is much higher than the resolution obtained in the DNA-based monovariate flow karyogram. Chromosome length appears to be an important factor in the resolution of the DNA vs CI-based flow… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 40 references

An instrument for real - time pulse - shape analysis of slit - scan flow cytometry signals

  • JA Aten
  • 1990

An instrument for real-time pulseshape analysis of slit-scan flow cytometry signals. Cytometry

  • Oven C van, JA Aten
  • 1990

Flow cytometric detection of isolated chromosomes following fluorescence hybridization

  • M Hausmann, G Dudin, +5 authors C Cremer
  • 1989

Detection of chromosome aberrations by flow cytometry as a test for radiation sensitivity

  • JA Aten, E Manders, C vanOven, W Rens, J Stap
  • Cytometry, Suppl
  • 1988

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