On-line biomass monitoring in bench-scale stirred bioreactors using parts of a liquid chromatography system


A cell density monitor, comprising parts of a liquid chromatography system, was adapted for on-line real-time measurement of bacterial cell density up to 75 g l−1. The device dilutes the sample containing cells and measures the absorbancy at 280 nm. This detector gives an excellent correlation with off-line measurements, good reproducibility, a low limit of… (More)
DOI: 10.1023/A:1021110730741


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