On-demand SSRI treatment of premature ejaculation: pharmacodynamic limitations for relevant ejaculation delay and consequent solutions.


INTRODUCTION Recently, the idea has emerged that on-demand use of serotonin reuptake inhibitors (SSRIs), particularly short half-life, should be equally effective in delaying ejaculation as daily SSRI treatment of premature ejaculation. AIM To provide evidence that SSRI-induced ejaculation delay is mainly dependent on pharmacodynamic properties of the… (More)


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