On cytoadhesion of Plasmodium vivax: raison d'être?

  title={On cytoadhesion of Plasmodium vivax: raison d'{\^e}tre?},
  author={Fabio T. M. Costa and Stefanie Lopes and Mireia Ferrer and Juliana Almeida Leite and Lorena Mart{\'i}n-Jaular and M Del Pilar Bernabeu and Paulo Afonso Nogueira and Maria Paula Gomes Mour{\~a}o and Carmen Fern{\'a}ndez-Becerra and Marcus Vin{\'i}cius Guimar{\~a}es de Lacerda and Hernando A Del Portillo},
  journal={Memorias do Instituto Oswaldo Cruz},
  volume={106 Suppl 1},
It is generally accepted that Plasmodium vivax, the most widely distributed human malaria parasite, causes mild disease and that this species does not sequester in the deep capillaries of internal organs. Recent evidence, however, has demonstrated that there is severe disease, sometimes resulting in death, exclusively associated with P. vivax and that P. vivax-infected reticulocytes are able to cytoadhere in vitro to different endothelial cells and placental cryosections. Here, we review the… CONTINUE READING

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The infection of reticulocytes by Plasmodium vivax

  • SK Kitchen
  • Am J Trop Med Hyg 18: 347.
  • 1938
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