On cross-priming of MHC class I-specific CTL: rule or exception?

@article{Zinkernagel2002OnCO,
  title={On cross-priming of MHC class I-specific CTL: rule or exception?},
  author={Rolf Martin Zinkernagel},
  journal={European journal of immunology},
  year={2002},
  volume={32 9},
  pages={
          2385-92
        }
}
It has been generally accepted as a rule that peptides binding to MHC class I molecules are derived from proteins synthesized within the cell, including peptides of genuine cellular origin as well as those encoded by viruses or other intracellular infectious agents. In contrast, MHC class II molecules, in general, bind peptides derived from exogenous proteins that have been processed via phago-lysozomes and replace the invariant chain clip fragment associated with class II molecules [1, 2]. MHC… CONTINUE READING
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Uncertainties – Discrepancies in Immunol

  • M. Kovacsovics-Bankowski, K. Clark, B. Benacerraf, K. L. Rock
  • Immunol . Rev .
  • 2002

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