On consanguineous marriages and the genetic load

  title={On consanguineous marriages and the genetic load},
  author={R. Murgai S. Chakraborty and Aravinda Chakravarti},
  journal={Human Genetics},
It has been reported that studies of the genetic consequences of inbreeding should adopt a different strategy in populations having a relatively old inbreeding history and where inbreeding levels have varied orver time. This contention is tested with a series of 39,495 single-birth records from Bombay, India, collected in a World Health Organization survey on congenital malformations. Our analysis reveals that: 1. the incidence of major malformations is significantly higher among the inbred… CONTINUE READING


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Showing 1-10 of 14 references

Inbreeding in India.

Eugenics quarterly • 1966
View 3 Excerpts
Highly Influenced

2. The concept of genetic load: a reply.

American journal of human genetics • 1963
View 3 Excerpts
Highly Influenced

Empirical risks in consanguineous marriages: sex ratio, malformation, and viability.

American journal of human genetics • 1958
View 1 Excerpt
Highly Influenced

Effect of inbreeding on congenital malformation

L. D. Sanghvi, N. N. Perin
A Burg Wartenstein Symposium Series No • 1974

Basic tabulations in respect of consecutive post 28week births recorded in the co - operating centres

A. C. Stevenson, H. A. Johnston, D. R. Golding, M. I. P. Stewart
Suppl . to Vol . 34 of Bulletin of the World Health Organization • 1966

Frequence et nature des anomalies dans les familles consanguines

J. Sutter, L. Tabah
World Health Organization Comparative Study of Congenital Malformations • 1966

The genetic consequences of inbreeding and outbreeding

L. D. Sanghvi
Eug . Quart . • 1966

Consanguineous marriages and the genetic load due to lethal genes in Kerala

H. Krieger, S. Kumar, R. A. Pal, M. S. Swaminathan
Cold Spring Harbor Symp . Quant . Biol . • 1964

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