On board a raft or boat in the retrovirus sea.

  title={On board a raft or boat in the retrovirus sea.},
  author={Jan Svoboda},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={113 15},
This article summarizes the essential steps in understanding the chicken Rous sarcoma virus (RSV) genome association with a nonpermissive rodent host cell genome. This insight was made possible by in-depth study of RSV-transformed rat XC cells, which were called virogenic because they indefinitely carry virus genetic information in the absence of any infectious virus production. However, the virus was rescued by association of XC cells with chicken fibroblasts, allowing cell fusion between both… CONTINUE READING
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