On The Occurrence Of A Factor In Human Serum Activating The Specific Agglutintion of Sheep Blood Corpuscles

  title={On The Occurrence Of A Factor In Human Serum Activating The Specific Agglutintion of Sheep Blood Corpuscles},
  author={Erik Waaler},

Insights of rheumatoid arthritis biomarkers

Abstract Rheumatoid arthritis is a chronic, autoimmune connective tissue disease. In addition to joint involvement, extra-articular changes and organ complications also occur in the course of the

Relación entre los polimorfismos genéticos relacionados con el transporte celular, poliglutamación y metabolismo del metotrexato y la respuesta terapéutica en artritis reumatoide

Los mejores resultados se consiguen con un inicio temprano de una estrategia de tratamiento por objetivos y un seguimiento estrecho that permitan controlar rapida y eficazmente el proceso inflamatorio.

Implications of the autoantibodies in the diagnosis of rheumatic diseases

Poroby reumatyczne to roznorodna pod wzgledem objawow klinicznych grupa schorzen, w patogenezie ktorych istotną role odgrywają procesy autimmunologiczne w rozpoznaniu reumatoidalnego zapalenia stawow.

From risk to chronicity: evolution of autoreactive B cell and antibody responses in rheumatoid arthritis

The latest insights into how autoantibodies and autoreactive B cells relate to the disease process in rheumatoid arthritis, from the development of pre-disease seropositivity to the onset of overt symptoms and the maintenance of disease chronicity are discussed.

B Cells on the Stage of Inflammation in Juvenile Idiopathic Arthritis: Leading or Supporting Actors in Disease Pathogenesis?

Evidence from the literature suggests that B cells might have indeed a relevant role in JIA pathophysiology, and B cell depletion therapy with rituximab has been shown to be an effective and well-tolerated treatment in children with JIA, which further supports B cell intervention in disease development.

Autoantibodies and Rheumatologic Manifestations in Hepatitis C Virus Infection

In patients with HCV, rheumatic manifestations are mostly mediated by immunological mechanisms, rather than being related to the viral infection of extrahepatic tissues, thus complicating a differential diagnosis between primitive and HCV-related disorders.


The signatures are reliable prognostic and predictive tools for disease recurrence in patients with stage II and III Gastric cancer and could add predictive value to traditional prognostic factors.

Objective and noninvasive biochemical markers in rheumatoid arthritis: where are we and where are we going?

A narrative overview of different classes of markers, such as autoantibodies, citrulline products, markers of tissue turnover and cytokines, that have been tested in clinical cohorts or trials including RA patients are provided.


HRCT chest is the most sensitive tool for early diagnosis of ILD, while DLCO is most sensitive for monitoring the prognosis.