On Guanidinium and Cellular Uptake

Abstract

Guanidinium-rich scaffolds facilitate cellular translocation and delivery of bioactive cargos through biological barriers. Although impressive uptake has been demonstrated for nonoligomeric and nonpept(o)idic guanidinylated scaffolds in cell cultures and animal models, the fundamental understanding of these processes is lacking. Charge pairing and hydrogen… (More)
DOI: 10.1021/jo501101s

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Cite this paper

@inproceedings{Wexselblatt2014OnGA, title={On Guanidinium and Cellular Uptake}, author={Ezequiel Wexselblatt and Jeffrey D. Esko and Yitzhak Tor}, booktitle={The Journal of organic chemistry}, year={2014} }